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Table 1 Demographic and clinical features of patients

From: Psychometric properties of the thyroid-specific quality of life questionnaire ThyPRO in Singaporean patients with Graves’ disease

Characteristics Subjects (n = 47)
Female, n (%) 35 (74.5)
Chinese, n (%) 43 (91.5)
Malay, n (%) 4 (8.5)
Smoking, n (%)
 Non-smoker 29 (69.1)
 Ex-smoker 9 (20.5)
 Current smoker 4 (9.1)
Presence of family history of thyroid disease, n (%) 24 (53.3)
Mean age at diagnosis, years (SD) 38.5 (14.1)
Mean duration of condition, years (SD) 5.5 (10.2)
Immunological diagnosis
 Thyrotropin Stimulating Hormone Receptor Antibody Positive 46 (97.9)
 Thyroid Stimulating Immunoglobulin Positive 1 (2.1)
Symptoms of hyperthyroidism
 General, n (%) 31 (67.4)
 Cardiorespiratory, n (%) 34 (72.3)
 Gastrointestinal, n (%) 33 (70.2)
 Neurological, n (%) 28 (59.6)
 Eye, n (%) 12 (25.5)
 Constitutional, n (%) 14 (29.8)
Signs of hyperthyroidism
 Heart rate, bpm (SD) 91 (21.6)
 Goitre, n (%) 28 (62.2)
 Clinical hyperthyroidism, n (%) 31 (70.5)
Biochemical and Ultrasound
 Mean free thyroxine, pmol/L (SD) 45.9 (22.0)
 Median TSH, mIU/L (IQR)- Range 0.00249–0.22 0.02 (0.01–0.03)
 Mean TRAb, IU/L (SD) 16.0 (13.3)
Thionamide treatment
 Propylthiouracil, mg/day (SD) 90 (42)
 Carbimazole, mg/day (SD) 16 (8)