Psychometric properties of FACIT-Fatigue in systemic lupus erythematosus: a pooled analysis of three phase 3 randomised, double-blind, parallel-group controlled studies (BLISS-SC, BLISS-52, BLISS-76)

Journal of Patient-Reported Outcomes

Table 5 Spearman correlations between change from baseline in FACIT-Fatigue and various measures (Week 52)

PRO scale	BLISS-SC (n = 654–662)	BLISS-52 (n = 665–688)	BLISS-76 (n = 606–613)	Pooled (N = 1271–1958)
SF-36v2
Physical component score	N/A	0.48	0.48	0.48
Mental component score	N/A	0.54	0.54	0.53
Physical functioning	N/A	0.42	0.45	0.43
Role physical	N/A	0.46	0.54	0.50
Bodily pain	N/A	0.49	0.50	0.50
General health	N/A	0.46	0.45	0.45
Vitality	N/A	0.63	0.70	0.67
Social functioning	N/A	0.46	0.54	0.50
Role emotional	N/A	0.43	0.43	0.42
Mental health	N/A	0.48	0.48	0.48
SELENA-SLEDAI	−0.12	−0.10	−0.08	−0.10
PGA	−0.12	−0.17	−0.31	−0.20

Spearman correlations were assessed as weak (r < 3.0), moderate (r ≥ 0.3 and < 0.5) or strong (r ≥ 0.5)
FACIT Functional Assessment of Chronic Illness Therapy, N/A Not assessed, PGA Physician’s Global Assessment, PRO Patient-reported outcomes, SELENA-SLEDAI Safety of Estrogens in Lupus Erythematosus National Assessment-Systemic Lupus Erythematosus Disease Activity Index, SF-36v2 Short Form-36 Health Survey Version 2