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Table 3 Spearman correlations between mean FACIT-Fatigue scores, and number of SLE flares by severity and trial

From: Psychometric properties of FACIT-Fatigue in systemic lupus erythematosus: a pooled analysis of three phase 3 randomised, double-blind, parallel-group controlled studies (BLISS-SC, BLISS-52, BLISS-76)

Trial period Flare severity BLISS-SC BLISS-52 BLISS-76
   n = 763 n = 886 n = 828
Number of FACIT-Fatigue assessments   5341 6202 8280
Weeks 0–52 All flares −0.09 −0.14 −0.20
Mild/moderate −0.09 − 0.11 − 0.19
Severe −0.02 − 0.10 − 0.06
   n = 763 n = 818 n = 753
Number of FACIT-Fatigue assessments   2289 2454 3765
Weeks 24–52 All flares −0.14 −0.16 −0.25
Mild/moderate −0.14 −0.16 − 0.25
Severe −0.04 −0.05 − 0.06
  1. Correlations: < 0.3, weak; ≤0.3 to < 0.6, moderate-strong; ≥0.6, strong
  2. The FACIT-Fatigue scores are patient level mean scores at two time points, mean of 0- and 52-week scores and mean of 24- and 52-week scores
  3. FACIT Functional Assessment of Chronic Illness Therapy, SLE systemic lupus erythematosus