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Table 5 Summary statistics for the TNAS v3.0 and CIPN20 subscales at the initial assessment, by cohort

From: The Treatment-induced Neuropathy Assessment Scale (TNAS): a psychometric update following qualitative enrichment

 

Treatment Groups

 

Bortezomib

n = 20

Oxaliplatin

n = 20

Taxane–Platinum

n = 20

p-value*

TNAS V3.0

Mean (SD)

Mean (SD)

Mean (SD)

 

TNAS global

2.90 (1.51)

3.10 (2.09)

4.60 (2.56)

0.026

TNAS sensory

3.13 (1.63)

3.34 (2.04)

4.84 (2.55)

0.025

TNAS interference

2.40 (2.04)

2.62 (2.5)

4.13 (2.97)

0.070

EORTC-CIPN20**

 CIPN20 sensory

17.15 (4.74)

18.05 (5.48)

19.85 (7.03)

0.336

 CIPN20 motor

13.45 (4.11)

12.95 (3.65)

14.35 (6.40)

0.656

 CIPN20 autonomic

3.80 (1.4)

3.90 (1.37)

3.20 (1.40)

0.236

  1. Abbreviation: TNAS Treatment-induced Neuropathy Assessment Scale, EORTC-CIPN20 European Organization for Research in the Treatment of Cancer – Chemotherapy –Induced Peripheral Neuropathy
  2. * P-values based on one way analysis of variance comparing the three treatment groups
  3. **EORTC-CIPN20 scores are based on raw scale scores