Table 6 Responsiveness of PROMIS Fatigue Short Form 6a at months 3 and 6
Time | Sample | N | Mean (SD) | t-value (p-value)† | Effect size (Cohen’s d)b | ||
|---|---|---|---|---|---|---|---|
Baseline | Post-baselinea | Change (SD) | |||||
Month 3 | Total Sample | 728 | 63.2 (7.5) | 57.0 (9.7) | −6.2 (9.8) | 17.12 (< 0.0001) | −0.83 |
Placebo | 314 | 62.4 (7.4) | 58.2 (9.7) | −4.2 (9.3) | 8.02 (<.0001) | −0.57 | |
150 mg | 216 | 64.0 (7.8) | 57.4 (9.5) | −6.7 (10.0) | 9.79 (<.0001) | −0.85 | |
200 mg | 198 | 63.6 (7.3) | 54.6 (9.5) | −9.0 (9.9) | 12.90 (<.0001) | −1.25 | |
Month 6 | Total Sample | 577 | 63.1 (7.5) | 56.3 (10.1) | −6.8 (10.4) | 15.76 (< 0.0001) | −0.91 |
Placebo | 246 | 62.5 (7.7) | 58.3 (10.0) | −4.2 (9.8) | 6.73 (<.0001) | −0.55 | |
150 mg | 170 | 63.6 (7.7) | 56.6 (9.4) | −7.0 (9.9) | 9.24 (<.0001) | −0.91 | |
200 mg | 161 | 63.5 (7.2) | 52.9 (10.0) | −10.6 (10.7) | 12.64 (<.0001) | −1.48 | |