Table 2 QOL Scores by Maximum Grade Adverse Event Per Week
Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 0 | Grade 1 | Grade 2 | Grade 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Week | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P-value | Week | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P-value | ||
Overall QOL | 0 | 78.8 (20.0) | 75.7 (16.3) | 61.4 (24.1) | 0.15 | Pain Frequency | 0 | 84.0 (18.7) | 74.3 (23.8) | 52.9 (39.9) | 0.09 | ||
1 | 81.7 (20.4) | 74.6 (24.1) | 64.5 (20.1) | 0.03 | 1 | 72.4 (34.0) | 75.8 (28.3) | 74.0 (23.5) | 0.81 | ||||
3 | 79.3 (16.7) | 64.7 (21.4) | 68.0 (32.7) | 0.09 | 3 | 78.0 (21.1) | 65.0 (23.0) | 74.0 (20.7) | 0.15 | ||||
5 | 63.3 (15.3) | 65.2 (21.4) | 60.7 (22.8) | 0.72 | 5 | 50.0 (28.3) | 64.1 (24.2) | 61.9 (25.9) | 0.69 | ||||
7 | 62.1 (20.0) | 77.5 (20.6) | 0.16 | 7 | 65.7 (26.5) | 55.0 (26.5) | 0.35 | ||||||
Mental WB | 0 | 80.6 (20.3) | 80.5 (14.7) | 71.4 (21.2) | 0.43 | Pain Severity | 0 | 86.3 (15.0) | 78.6 (17.7) | 68.6 (34.4) | 0.22 | ||
1 | 81.7 (20.9) | 79.2 (17.4) | 66.0 (19.0) | 0.02 | 1 | 86.3 (17.5) | 77.9 (24.8) | 77.0 (22.0) | 0.32 | ||||
3 | 78.7 (16.4) | 73.7 (18.9) | 78.0 (29.5) | 0.49 | 3 | 80.0 (15.1) | 67.9 (21.3) | 66.0 (28.8) | 0.20 | ||||
5 | 63.3 (5.8) | 71.2 (22.0) | 68.1 (23.4) | 0.57 | 5 | 60.0 (28.3) | 71.0 (21.0) | 68.8 (20.9) | 0.67 | ||||
7 | 69.4 (18.8) | 85.0 (12.9) | 0.10 | 7 | 69.4 (23.2) | 60.0 (18.3) | 0.34 | ||||||
Physical WB | 0 | 69.4 (19.1) | 70.5 (17.2) | 48.6 (19.5) | 0.04 | Fatigue | 0 | 66.0 (27.1) | 55.7 (26.9) | 52.9 (27.5) | 0.22 | ||
1 | 71.1 (24.7) | 71.3 (23.3) | 56.0 (17.9) | 0.03 | 1 | 60.6 (25.3) | 59.2 (26.2) | 42.5 (17.4) | 0.08 | ||||
3 | 70.7 (17.5) | 63.7 (20.5) | 62.0 (25.9) | 0.58 | 3 | 57.3 (27.9) | 50.3 (25.8) | 60.0 (15.8) | 0.50 | ||||
5 | 60.0 (20.0) | 61.5 (21.9) | 54.4 (25.8) | 0.62 | 5 | 33.3 (11.5) | 49.8 (24.2) | 50.6 (18.4) | 0.36 | ||||
7 | 57.9 (19.7) | 72.5 (17.1) | 0.16 | 7 | 44.7 (23.3) | 60.0 (34.6) | 0.48 | ||||||
Emotional WB | 0 | 75.6 (20.8) | 72.9 (17.1) | 58.6 (23.4) | 0.15 | Level of Support | 0 | 94.3 (11.4) | 94.3 (12.1) | 85.7 (29.9) | 0.94 | ||
1 | 77.2 (22.7) | 72.9 (21.8) | 67.0 (20.3) | 0.22 | 1 | 93.9 (16.1) | 94.6 (7.8) | 90.5 (15.4) | 0.31 | ||||
3 | 78.7 (13.0) | 70.3 (22.1) | 76.0 (33.6) | 0.44 | 3 | 95.0 (8.5) | 94.5 (10.3) | 94.0 (13.4) | 0.93 | ||||
5 | 66.7 (11.5) | 65.0 (21.6) | 66.3 (24.7) | 0.94 | 5 | 100.0 (0.0) | 91.2 (15.0) | 89.4 (15.3) | 0.30 | ||||
7 | 68.1 (19.9) | 77.5 (20.6) | 0.34 | 7 | 93.5 (11.4) | 96.7 (5.8) | 0.74 | ||||||
Social Activity | 0 | 71.2 (25.9) | 67.5 (20.5) | 48.6 (38.0) | 0.23 | Financial Concerns | 0 | 64.9 (31.9) | 63.8 (35.1) | 82.9 (37.3) | 0.21 | ||
1 | 63.9 (31.5) | 65.0 (27.0) | 55.5 (21.9) | 0.41 | 1 | 67.2 (33.7) | 66.7 (30.3) | 75.5 (26.8) | 0.68 | ||||
3 | 71.3 (21.0) | 54.5 (25.9) | 56.0 (31.3) | 0.11 | 3 | 64.7 (34.2) | 70.0 (31.5) | 76.0 (37.8) | 0.69 | ||||
5 | 66.7 (25.2) | 54.5 (25.9) | 46.3 (27.5) | 0.40 | 5 | 93.3 (11.5) | 69.8 (32.2) | 58.1 (32.3) | 0.10 | ||||
7 | 54.5 (23.0) | 62.5 (33.0) | 0.51 | 7 | 75.7 (26.1) | 60.0 (52.9) | 0.72 | ||||||
Spiritual WB | 0 | 81.5 (20.9) | 78.0 (17.9) | 70.0 (26.8) | 0.42 | Legal Concerns | 0 | 74.6 (34.0) | 72.4 (33.2) | 97.1 (7.6) | 0.07 | ||
1 | 82.8 (17.4) | 77.1 (25.6) | 74.7 (25.0) | 0.82 | 1 | 84.4 (25.0) | 77.1 (35.1) | 78.0 (32.5) | 0.77 | ||||
3 | 78.0 (17.4) | 76.5 (20.7) | 75.0 (37.9) | 0.89 | 3 | 66.0 (37.0) | 82.9 (28.2) | 90.0 (22.4) | 0.07 | ||||
5 | 90.0 (10.0) | 75.3 (21.7) | 72.0 (26.8) | 0.49 | 5 | 86.7 (23.1) | 78.8 (31.3) | 69.4 (34.7) | 0.52 | ||||
7 | 76.7 (20.9) | 85.0 (19.1) | 0.40 | 7 | 76.9 (32.1) | 47.5 (37.7) | 0.15 |