Table 3 Comparison between baseline and 6 months follow-up visit for PROMs and clinical outcomes
|  | Baseline Mean (±SD) | 6 months Mean (±SD) | Difference between the means (95% CI) | t | p |
|---|---|---|---|---|---|
PROMs | |||||
 WHOQOL-BREF | |||||
  Physical health | 72.09 (±14.99) | 69.86 (±16.29) | −2.23 (−6.14, 1.68) | − 1.17 | 0.25 |
  Psychological health | 76.85 (±16.11) | 72.38 (±17.42) | −4.48 (− 8.86, − 0.09) | − 2.10 | 0.05* |
  Social relationships | 78.70 (±13.54) | 76.85 (±13.54) | −1.85 (− 5.87, 2.17) | − 0.95 | 0.35 |
  Environmental health | 84.14 (±10.79) | 82.06 (±12.24) | −2.08 (−6.28, 2.12) | −1.02 | 0.32 |
 SIPP-RS | 25.52 (±5.07) | 24.93 (±5.35) | −0.59 (−2.02, 0.83) | − 0.86 | 0.40 |
 IBM-FRS | 33.89 (±3.75) | 33.30 (±4.58) | −0.59 (−1.53, 0.34) | −1.31 | 0.20 |
Clinical outcomes | |||||
 6MWD | 391.52 (±132.24) | 401.85 (±148.10) | 10.33 (−9.96, 30.63) | 1.05 | 0.30 |
 MFM | 83.87 (±12.85) | 85.46 (±12.19) | 1.58 (−0.58, 3.74) | 1.50 | 0.14 |