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Table 2 Descriptive Statistics for Total FACT-EGFRI 18 Scale and Subscale Scores*

From: A prospective study to validate the functional assessment of cancer therapy (FACT) for epidermal growth factor receptor inhibitor (EGFRI)-induced dermatologic toxicities FACT-EGFRI 18 questionnaire: SWOG S1013

 

Mean

(SD)

Day 1

Day 8

Day 15

Day 22

Day 29

Day 36

Day 43

Day 71

Day 99

Day 127

Alopecia

92.4

93.7

93.5

93.6

91.5

90.1

88.3

82.8

79.9

75.0

(18.4)

(16.5)

(16.5)

(17.5)

(17.9)

(18.0)

(21.7)

(26.6)

(28.5)

(30.6)

Dry skin

94.4

90.1

82.1

83.6

86.3

88.3

86.6

85.0

84.5

85.6

(8.7)

(13.9)

(21.7)

(19.3)

(16.9)

(11.5)

(12.6)

(16.1)

(13.4)

(17.4)

Hypertrichosis

96.7

96.1

94.3

95.4

97.4

97.3

95.8

87.8

91.7

86.4

(11.1)

(13.8)

(17.4)

(11.9)

(8.6)

(8.9)

(12.4)

(23.6)

(22.4)

(24.3)

Pain of skin

95.5

86.6

76.1

79.9

82.4

86.9

82.7

83.0

85.4

84.3

(11.4)

(18.4)

(23.7)

(22.7)

(20.0)

(12.2)

(16.9)

(18.5)

(16.6)

(18.5)

Paronychia

96.2

95.2

92.5

87.7

86.8

88.0

82.4

77.2

80.2

75.8

(9.9)

(10.3)

(14.2)

(20.6)

(20.3)

(16.4)

(22.6)

(25.3)

(26.3)

(24.6)

Pruritus

92.8

83.0

74

76.5

78.8

84.9

79.1

80.6

79.2

81.4

(15.1)

(22.4)

(24.2)

(23.4)

(21.4)

(12.8)

(18.3)

(18.6)

(19.4)

(20.5)

Rash

94.9

89.5

80.7

82.8

85.5

88.5

85.2

84.4

84.3

84.7

(8.2)

(13.9)

(20.7)

(18.9)

(15.8)

(9.7)

(13.1)

(16.6)

(14.5)

(16.9)

Total FACT- EGFRI 18

67.9

64.9

60.1

60.8

62.1

63.8

61.5

60.1

60.0

59.6

(5.3)

(8.1)

(11.8)

(10.8)

(9.0)

(6.0)

(8.6)

(11.0)

(9.9)

(11.6)

  1. *Higher FACT-EGFRI scores reflect better health-related quality of life