Table 3 Known-Groups Validity: PROMIS-PF and Worst Stiffness NRS
Pain Levela | Overall F-value (P-value) | P-valueb | |||||||||
Mild 1–4.9 | Moderate 5–6.9 | Severe > 7 | |||||||||
Missing N | N | LS mean (SE) | N | LS mean (SE) | N | LS mean (SE) | |||||
PROMIS Physical Functioning | |||||||||||
All Tumors | 10 | 39 | 39.85 (1.44) | 41 | 36.64 (1.51) | 30 | 33.74 (1.51) | 3.87 (0.0002) | 1: 0.0218 / 2:< 0.0001 / 3: 0.0750 | ||
Knee Tumors | 7 | 26 | 39.27 (1.69) | 22 | 36.44 (1.86) | 18 | 33.54 (1.67) | 2.39 (0.0196) | 1: 0.1669 / 2: 0.0025 / 3: 0.2480 | ||
Other (Non-Knee) Lower Extremity Tumors | 3 | 8 | 45.14 (3.59) | 16 | 42.46 (2.99) | 10 | 38.13 (2.92) | 2.51 (0.0412) | 1: 0.5264 / 2: 0.0713 / 3: 0.2444 | ||
Worst Stiffness NRS | |||||||||||
All Tumors | 8 | 39 | 4.09 (0.31) | 42 | 6.21 (0.32) | 31 | 7.79 (0.32) | 21.96 (< 0.0001) | 1:< 0.0001 / 2:< 0.0001 / 3:< 0.0001 | ||
Knee Tumors | 5 | 26 | 4.13 (0.39) | 23 | 5.89 (0.42) | 19 | 7.72 (0.38) | 11.76 (< 0.0001) | 1:< 0.0001 / 2:< 0.0001 / 3:< 0.0001 | ||
Other (Non-Knee) Lower Extremity Tumors | 3 | 8 | 3.13 (0.72) | 16 | 5.89 (0.60) | 10 | 7.55 (0.58) | 10.67 (< 0.0001) | 1:< 0.0001 / 2:< 0.0001 / 3: 0.0106 | ||
Tumor Volume Scorea | Overall F-value (P-value) | P-valueb | |||||||||
Small < 5 | Medium 5–10 | Large > 10 | |||||||||
Missing N | N | LS mean (SE) | N | LS mean (SE) | N | LS mean (SE) | |||||
PROMIS Physical Functioning | |||||||||||
All Tumors | 9 | 41 | 37.11 (1.75) | 33 | 37.28 (1.55) | 37 | 36.64 (1.72) | 1.19 (0.3047) | 4: 0.9923 / 5: 0.9397 / 6: 0.9031 | ||
Knee Tumors | 6 | 33 | 36.89 (1.97) | 23 | 35.77 (1.75) | 11 | 36.64 (2.43) | 0.87 (0.5680) | 4: 0.7806 / 5: 0.9939 / 6: 0.9312 | ||
Other (Non-Knee) Lower Extremity Tumors | 3 | 6 | 36.68 (4.07) | 7 | 40.37 (3.82) | 21 | 39.97 (2.96) | 1.35 (0.2681) | 4: 0.5196 / 5: 0.5144 / 6: 0.9881 | ||
Worst Stiffness NRS | |||||||||||
All Tumors | 10 | 42 | 5.63 (0.59) | 32 | 5.99 (0.53) | 36 | 6.00 (0.59) | 0.53 (0.8637) | 4: 0.7424 / 5: 0.7086 / 6: 0.9995 | ||
Knee Tumors | 6 | 34 | 5.93 (0.69) | 23 | 6.32 (0.62) | 10 | 6.00 (0.90) | 0.37 (0.9558) | 4: 0.7932 / 5: 0.9967 / 6: 0.9375 | ||
Other (Non-Knee) Lower Extremity Tumors | 4 | 6 | 7.55 (1.37) | 6 | 7.14 (1.32) | 21 | 6.87 (1.00) | 0.60 (0.7472) | 4: 0.9358 / 5: 0.7776 6: 0.9577 | ||
Stiffness Levela | Overall F-value (P-value) | P-valueb | |||||||||
Low 1–4.9 | Medium 5–6.9 | High > 7 | |||||||||
Missing N | N | LS mean (SE) | N | LS mean (SE) | N | LS mean (SE) | |||||
PROMIS Physical Functioning | |||||||||||
All Tumors | 10 | 34 | 39.77 (1.51) | 48 | 36.48 (1.49) | 28 | 34.03 (1.58) | 3.21 (0.0013) | 7: 0.0212 / 8: 0.0002 / 9: 0.1436 | ||
Knee Tumors | 7 | 20 | 38.21 (1.82) | 30 | 36.42 (1.68) | 16 | 33.14 (1.94) | 1.73 (0.0980) | 7: 0.4843 / 8: 0.0245 / 9: 0.1528 | ||
Other (Non-Knee) Lower Extremity Tumors | 3 | 10 | 47.41 (2.92) | 14 | 40.53 (2.55) | 10 | 39.21 (2.46) | 4.66 (0.0017) | 7: 0.0073 / 8: 0.0033 / 9: 0.7984 | ||
Physical Functioning Limitation Levela | Overall F-value (P-value) | P-valueb | |||||||||
No Limitation > 45 | Low 35–45 | Medium 30–35 | High < 30 | ||||||||
Missing N | N | LS mean (SE) | N | LS mean (SE) | N | LS mean (SE) | N | LS mean (SE) | |||
Worst Stiffness NRS | |||||||||||
All Tumors | 10 | 13 | 4.62 (0.67) | 62 | 5.52 (0.49) | 28 | 6.32 (0.50) | 7 | 7.31 (0.82) | 1.90 (0.0481) | 10: 0.4194 11: 0.0459 12: 0.0220 13: 0.2639 14: 0.1048 15: 0.6305 |
Knee Tumors | 7 | 7 | 5.07 (0.89) | 39 | 5.68 (0.63) | 18 | 6.24 (0.59) | 2 | 7.79 (1.45) | 0.90 (0.5469) | 10: 0.8758 11: 0.5640 12: 0.3940 13: 0.7772 14: 0.5292 15: 0.7645 |
Other (Non-Knee) Lower Extremity Tumors | 3 | 4 | 5.21 (1.13) | 18 | 7.29 (0.84) | 9 | 8.59 (1.10) | 3 | 9.85 (1.50) | 2.18 (0.0650) | 10: 0.2141 11: 0.0363 12: 0.0369 13: 0.4281 14: 0.2414 15: 0.7354 |