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Table 2 Baseline Demographic and Clinical Characteristics of Enrolled Patients

From: Responsiveness of PROMIS® to change in chronic obstructive pulmonary disease

Characteristic

Stable (n = 100)

Exacerbation (n = 85)

p-value

 

mean (sd) range

mean (sd) range

< 0.01

Age

64.6 (9.3)

60.5 (10.2)

Range: 43–85

Range: 41–88

BMI

31.10 (8.5)

32.10 (11.1)

0.51

Range: 18–65

Range: 16–79

Smoking pack year history

46.68 (27.3)

48.99 (34.5)

0.62

Range: 10–156

Range: 10–180

 

n (%)

n (%)

p-value

Age Category

  

< 0.01

 40–49 years

2 (2)

8 (9)

 

 50–59 years

28 (28)

37 (44)

 

 60–69 years

37 (37)

25 (29)

 

 70+ years

33 (33)

15 (18)

 

Gender (Female)

43 (43)

43 (51)

0.30

Race (White)

75 (75)

60 (73)

0.78

Percent predicted FEV1

  

0.41

  > = 80

4 (5)

2 (3)

 

 50–79

35 (42)

27 (39)

 

 30–49

33 (39)

23 (33)

 

  < 30

12 (14)

17 (25)

 

6 min walk (> 300 m)

46 (55)

17 (43)

0.20

Length of COPD diagnosis

  

0.03

  < 1 yr

4 (4)

14 (17)

 

 1–3 yrs

23 (23)

20 (24)

 

 3–5 yrs

15 (15)

14 (17)

 

  > 5 yrs

56 (57)

36 (43)

 

Exacerbations last 12 months

  

< 0.0001

 0

67 (68)

6 (7)

 

 1

17 (17)

24 (28)

 

 2 to 5

13 (13)

46 (54)

 

  > 6

2 (2)

9 (11)

 

COPD hospitalizations last 12 months

  

< 0.0001

 0

84 (87)

13 (15)

 

 1

9 (9)

39 (46)

 

 2 to 5

4 (4)

30 (36)

 

  > 6

0 (0)

2 (2)

 

COPD ED visits last 12 months

  

< 0.0001

 0

81 (83)

35 (41)

 

 1

9 (9)

23 (27)

 

 2 to 5

7 (7)

25 (29)

 

  > 6

1 (1)

2 (2)

 

COPD medicationsa

   

 Antibiotics

1 (1)

20 (24)

< 0.0001

 Beta agonists

94 (96)

80 (96)

0.87

 Inhaled steroids

59 (60)

52 (63)

0.74

 Systemic steroids

3 (3)

40 (48)

< 0.0001

 Anticholinergenics

72 (74)

64 (77)

0.65

GOLD classification

  

0.43

 GOLD 1 mild COPD

18 (19)

12 (17)

 

 GOLD 2 moderate COPD

36 (39)

24 (33)

 

 GOLD 3 severe COPD

25 (27)

28 (39)

 

 GOLD 4 very severe COPD

14 (15)

8 (11)

 
  1. aResponses are not mutually exclusive; participants could select more than one response