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Table 5 ASDD Construct Validity Correlations at Week 4 (Phase 2 data; N = 105 or Phase 3 data; N = 697)

From: Development and validation of the Axillary Sweating Daily Diary: a patient-reported outcome measure to assess axillary sweating severity

ASDD Item   HDSS Grade, Pearson correlation Sweat Production,a Pearson correlation DLQI/C-DLQI, Spearman correlation Weekly Impact Summary, Pearson correlation PGIC, Spearman correlation
Week 4 Average
 Axillary Sweating Severity (Item 2) Phase 2 0.73* 0.33* N/A 0.52* 0.62*
Phase 3 9–15yo 0.71* 0.17 0.51* N/A N/A
Phase 3 ≥ 16yo 0.70* 0.18* 0.61* 0.66* 0.70*
 Impact (Item 3) Phase 2 0.71* 0.24* N/A 0.62* 0.65*b
Phase 3 Pooled 0.72* 0.13* 0.65* 0.68* 0.65*
 Bothersomeness (Item 4) Phase 2 0.79* 0.27* 0.64* 0.70*b
Phase 3 Pooled 0.74* 0.13* 0.66* 0.69* 0.66*
Change from Baseline to Week 4
 Axillary Sweating Severity (Item 2) Phase 2 0.57* 0.17 N/A 0.65* 0.48*
Phase 3 9–15yo 0.71* 0.17 0.51* N/A N/A
Phase 3 ≥ 16yo 0.70* 0.18 0.63* 0.62* 0.68*
 Impact (Item 3) Phase 2 0.51* 0.05 N/A 0.57* 0.27*
Phase 3 Pooled 0.64* 0.01 0.51* 0.65* 0.57*
 Bothersomeness (Item 4) Phase 2 0.58* 0.13 N/A 0.61* 0.31*
Phase 3 Pooled 0.65* 0.02 0.53* 0.65* 0.59*
  1. ASDD Axillary Sweating Daily Diary, HDSS Hyperhidrosis Disease Severity Scale, PGIC Patient Global Impression of Change
  2. *p ≤ 0.05
  3. a Measured gravimetrically
  4. b Weekly average for PGIC is not applicable
  5. Entries marked N/A indicate that the assessment was not performed for that study and/or population
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