Skip to main content

Table 3 Results of Psychometric Analysis of Real-World Daily eDiary Data

From: Exploring content and psychometric validity of newly developed assessment tools for itch and skin pain in atopic dermatitis

Parameter Itch NRS[a] Skin Pain NRS[a]
Test-retest reliability[b] (n = 31)
 Week 1 to Week 2 Average 0.95 0.97
 Day 7 to Day 14 0.94 0.91
Concurrent validity[c]
 POEM (Week 1; n = 74) 0.80 0.75
 POEM (Week 2; n = 66) 0.84 0.77
 PGIS (Week 1; n = 55) 0.72 0.68
 PGIS (Week 2; n = 42) 0.74 0.65
 DLQI Summary Score (Adult population; n = 33–53) 0.59–0.74 0.57–0.73
 CDLQI Summary Score (Adolescent population; n = 9–19) 0.76–0.89 0.77–0.91
Responsiveness[d]
 Week 1 to Week 2 Average p = 0.02 p = 0.003
  Decline ES = 1.21 (n = 5) ES = 1.09 (n = 5)
  No Decline ES = 0.41 (n = 24) ES = 0.34 (n = 39)
 Day 7 to Day 14 p = 0.25 p = 0.42
  Decline ES = 0.40 (n = 5) ES = 0.24 (n = 5)
  No Decline ES = 0.08 (n = 24) ES = 0.04 (n = 24)
  1. Abbreviations: CDLQI Children’s Dermatology Life Quality Index, DLQI Dermatology Life Quality Index, NRS Numeric rating scale, PGIS Patient Global Impression of Severity, POEM Patient Oriented Eczema Measure, ES Effect size
  2. [a]The NRS scales ranged from 0 to 10
  3. [b]Test-retest calculation assessed score changes from Day 7 and Day 14 and the Week 1 to Week 2 average in patients who showed a 0- or 1-point change on the PGIS scale
  4. [c]Correlations performed on Day 1, 7, 14, and the Week 1 to Week 2 average except for PGIS, which was only collected at Day 7 and 14
  5. [d]p-value from test for difference in mean score change of participants who scored above and below 4 on the PGIC between Weeks 1 and 2 and Day 7 and Day 14