From: Evaluating minimal important differences and responder definitions for the asthma symptom diary in patients with moderate to severe asthma
ACQ Group
Week 12
Week 24
1 Change ≤ −1.0 [Responder]
−2.34
−3.22
2 Change −0.5 to −1.0 [MID]
− 1.75
−1.98
3 Change ≥ − 0.5
− 0.61
−0.35
Model p-value
< 0.0001
Significant contrasts (p < 0.01)
1v3; 2v3
1v2; 1v3; 2v3