Skip to main content

Table 2 Responsiveness of ASD Symptomatic Days in a 7-Day Period at Weeks 12 and 24

From: Evaluating minimal important differences and responder definitions for the asthma symptom diary in patients with moderate to severe asthma

  Responders Mean (SE) Non-Responders Mean (SE) Difference P-Value
Week 12
 ACQ > 0.5 −2.21 (0.16) −0.57 (0.18) −1.64 p < 0.001
 Effect size 0.73 0.19
 ACQ > 1.0 −2.35 (0.20) −0.90 (0.16) −1.45 p < 0.001
 Effect size 0.78 0.30
 PGA −2.34 (0.16) −0.45 (0.17) −1.86 p < 0.001
 Effect size 0.78 0.15
Week 24
 ACQ > 0.5 −2.86 (0.18) − 0.28 (0.28) − 2.57 p < 0.001
 Effect size 0.95 0.09
 ACQ > 1.0 −3.21 (0.21) −0.77 (0.20) −2.44 p < 0.001
 Effect size 1.07 0.26
 PGA −2.97 (0.19) −0.45 (0.23) −2.52 p < 0.001
 Effect size 0.99 0.15
  1. Symptomatic Days defined as mean of the 10 ASD daily symptom items ≥1, otherwise non-Symptomatic Day