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Table 1 Responsiveness of the Average 7-Day ASD Score at Weeks 12 and 24

From: Evaluating minimal important differences and responder definitions for the asthma symptom diary in patients with moderate to severe asthma

  Responders Mean (SE) Non-Responders Mean (SE) Difference P-Value
Week 12
 ACQ > 0.5 −0.49 (0.03) − 0.05 (0.03) − 0.43 p < 0.001
 Effect size 0.82 0.08
 ACQ > 1.0 −0.54 (0.03) −0.13 (0.03) − 0.42 p < 0.001
 Effect size 0.90 0.22
 PGA −0.48 (0.03) −0.07 (0.03) − 0.41 p < 0.001
 Effect size 0.80 0.12
Week 24
 ACQ > 0.5 −0.59 (0.03) −0.06 (0.03) − 0.53 p < 0.001
 Effect size 0.98 0.10
 ACQ > 1.0 −0.68 (0.04) −0.15 (0.03) − 0.53 p < 0.001
 Effect size 1.13 0.25
 PGA −0.60 (0.03) −0.10 (0.04) − 0.49 p < 0.001
 Effect size 1.00 0.17