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Table 5 Differences in WPAI scores between UC patient subgroups differing on health status

From: Psychometric validation of the work productivity and activity impairment questionnaire in ulcerative colitis: results from a systematic literature review

  Group mean differences in WPAI domain scores
Study N Predictor Comparison Absenteeism Presenteeism OWI Activity Impairment
Gibson 2014 [31] 175 Remission status (partial Mayo) Active vs Remission 20.3 13.4 17.2 27.8
Vaizey 2014 [34] 173 Remission status (partial Mayo) Active vs Remission 22.8 21.2 26.4 29.7
Katz Avitan 2016 [39] 150 Remission status (SCCAI) Active vs Remission 24.5 36.7 42.1
van Assche 2015 [35] 242 Remission status (self-perceived) Active vs Remission 10.4 22.0 23.0 24.0
Yarlas 2015b [37] 180 Remission status, Month 12 (UC-DAI) Active vs Remission 11.7 25.6 34.3 26.5
Yarlas 2015b [37] 258 Remission status, Week 8 (UC-DAI) Active vs Remission 7.4 22.6 26.7 26.0
Yarlas 2014 [41] 180 Remission status (UC-DAI) Active vs Remission 5.0 5.3 11.1 9.7
Yarlas 2014 [41] 180 Improved rectal bleeding (UC-DAI) Not improved vs improved 6.3 7.8 12.2 12.3
Yarlas 2014 [41] 180 Improved stool frequency (UC-DAI) Not improved vs improved 12.5 13.8 20.0 19.2
Yarlas 2015a [36] 146 Clinical symptom recurrence (UC-DAI) Recurrent vs Non-recurrent −0.9 12.7 12.5 9.2
Cohen 2014 [30] 95 Fatigue (FACIT-Fatigue) Fatigue vs Non-fatigue 11.3 23.9 23.8 25.7
Weighted mean differencea 11.7 18.5 22.7 21.3
Median difference 11.3 21.2 23.0 24.9
Percentage of values exceeding CIC 73% 91% 100% 100%
  1. CIC clinically important change; FACIT Functional Assessment of Chronic Illness Therapy; OWI Overall Work Impairment; SCCAI Simple Clinical Colitis Activity Index; UC, ulcerative colitis; UC-DAI Ulcerative Colitis – Disease Activity Index; WPAI Work Productivity and Activity Impairment questionnaire
  2. aWeighted by sample size
  3. --Reported value were not within the valid range (i.e., was > 100)
  4. Values printed in BOLD indicate mean differences exceeding the CIC threshold of 7% [27]