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Table 6 Anchor-based CID estimates based on changes from post-intervention and six month follow-up for the 37-item FACT-Cog total score

From: Important differences and meaningful changes for the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog)

EORTC change N (%) Mean change in FACT-Cog (SD) CID Estimatea Standardized effect size (% of scale)
T2:ρ  = 0.58
 Much better 92 (48) 31.3 (25.2)   
 Minimally better 50 (26) 16.5 (16.7)   
 No change 39 (20) 4.5 (15.9) 12.0 0.46 (9.1)
 Minimally worse 10 (5) 4.6 (18.1)   
 Much worse 1 (0.5) 15 (−)   
T3:ρ = 0.63
 Much better 85 (47) 33.0 (23.8)   
 Minimally better 56 (31) 17.9 (17.0)   
 No change 35 (19) 7.5 (16.2) 10.4 0.40 (7.0)
 Minimally worse 6 (3) −16.7(16.1)   
 Much worse 1 (0.6) 10 (−)   
  1. a|Min better – No change| in mean change in FACT-Cog