Table 5 Anchor-based CID estimates for improvement for the FACT-Cog total score (33 item) and FACT-Cog-PCI based on changes from baseline at post-intervention (T2) and six month follow-up (T3) and secondary anchor FACT-G. Correlations, ρ, are for the change in the FACT-Cog total score or PCI subscale and the categorized anchor changes
FACT-Cog scale | Time, Anchor | Anchor changea | N (%) | Mean change in FACT-Cog (SD) | MCT Estimateb | Standardized effect size | % of scale |
|---|---|---|---|---|---|---|---|
Total score | T2, FACT-G | ρ = 0.44 | |||||
Much better | 73 (38) | 28.7 (22.5) | |||||
Minimally better | 27 (14) | 18.5 (21.1) | 9.9 (9.1) | 0.43 (0.40) | 7.5 (6.9) | ||
No change | 43 (22) | 8.6 (12.4) | |||||
Minimally worse | 26 (14) | 6.9 (17.0) | |||||
Much worse | 13 (7) | 12.9 (17.2) | |||||
T3, FACT-G | ρ = 0 0.47 | ||||||
Much better | 57 (31) | 30.7 (22.6) | |||||
Minimally better | 35 (19) | 21.2 (18.6) | 6.1 (5.5) | 0.42 (0.24) | 4.7 (4.1) | ||
No change | 38 (21) | 15.1 (14.5) | |||||
Minimally worse | 22 (13) | 10.8 (18.0) | |||||
Much worse | 20 (12) | 5.6 (20.4) | |||||
FACT-Cog PCI | T2, FACT-G | ρ = −0.34 | |||||
Much better | 73 (38) | −16.5 (14.8) | |||||
Minimally better | 27 (14) | −11.0 (14.5) | |||||
No change | 43 (22) | −5.3 (10.6) | 6.3 (4.4) | 0.32 (0.30) | 6.6 (6.1) | ||
Minimally worse | 26 (14) | −10.5 (10.6) | |||||
Much worse | 13 (7) | −18.0 (14.3) | |||||
T3, FACT-G | ρ = −0.38 | ||||||
Much better | 57 (31) | −18.0 (14.4) | |||||
Minimally better | 35 (19) | −13.5 (11.7) | |||||
No change | 38 (21) | −10.4 (9.1) | 3.1 (3.1) | 0.21 (0.21) | 4.4 (4.4) | ||
Minimally worse | 22 (13) | −8.3 (12.1) | |||||
Much worse | 20 (12) | −5.1 (12.0) | |||||