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Table 4 Distribution-based CID (SD multiples) and MCT lower limit (SEM) estimates for the FACT-Cog total score and perceived cognitive impairments subscale

From: Important differences and meaningful changes for the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog)

 

N

SD

One-third SD

One-half SD

1 SEM, ρT-RT = 0.74

1 SEM, ρT-RT  = 0.70

FACT-Cog score (33 items)

 T1: Baseline

242

23.13

7.7

11.6

11.8

12.7

 T2: Post-intervention

192

26.31

8.8

13.2

13.4

14.4

 T3: Six-month follow-up

184

26.29

8.8

13.1

13.4

14.4

 Mean

 

25.24

8.4

12.6

12.9

13.8

FACT-Cog PCI

 T1: Baseline

242

14.77

4.9

7.7

7.5

8.1

 T2: Post-intervention

192

16.61

5.5

8.8

8.4

9.1

 T3: Six-month follow-up

184

16.17

5.4

8.8

8.2

8.9

 Mean

 

15.85

5.3

7.9

8.1

8.7

  1. Definitions: SD Standard deviation, SEM Standard error of measurement = σ√(1 − ρT-RT)