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Table 1 Demographics of survey respondents by level of comorbidity medication adherence

From: The relationship between comorbidity medication adherence and health related quality of life among patients with cancer

  Overall N = 1847 Low Adherence n = 508 Moderate/ High Adherence n = 1212 P value
Cancer type, n (%)
 Metastatic breast cancer 700 (37.9) 176 (34.7) 482 (39.8) 0.137
 Metastatic colorectal cancer 524 (28.4) 153 (30.1) 336 (27.7)  
 Metastatic lung cancer 623 (33.7) 179 (35.2) 394 (32.5)  
Demographic Characteristics
 Age, years, mean [SD] 69.2 [9.20] 68.5 [9.88] 69.5 [8.68] 0.043
 Sex female, n (%) 1233 (66.8) 324 (63.8) 827 (68.2) 0.073
 Race/Ethnicity (Medicare only), n (%)
  White 1379 (84.9) 373 (85.7) 910 (84) 0.767
  Non-white 240 (13.0) 60 (11.8) 170 (14.0)  
  Unknown 5 (0.3) 2 (0.5) 3 (0.3)  
 Marital Status, n (%)
  Married 1051 (57.2) 298 (59.1) 679 (56.3) 0.558
  Divorced 268 (14.6) 71 (14.1) 180 (14.9)  
  Separated 24 (1.3) 6 (1.2) 15 (1.2)  
  Widowed 368 (20.0) 91 (18.1) 256 (21.2)  
  Living in a marriage-like relationship 49 (2.7) 17 (3.4) 28 (2.3)  
  Single, Never Married 77 (4.2) 21 (4.2) 49 (4.1)  
  Lives alone, n (%) 444 (24.0) 108 (21.3) 310 (25.6) 0.057
 Geographic Region, n (%)
  Northeast 29 (1.6) 9 (1.8) 16 (1.3) 0.432
  Midwest 453 (24.5) 114 (22.4) 306 (25.2)  
  South 1220 (66.1) 340 (66.9) 801 (66.1)  
  West 145 (7.9) 45 (8.9) 89 (7.3)  
 Medicare Advantage (vs. Commercial), n (%) 1629 (88.2) 436 (85.8) 1087 (89.7) 0.022
 Dual eligibility for Medicare and Medicaid 192 (11.8) 41 (9.4) 32 (12.5) 0.094
Clinical Characteristics
 Comorbid conditions (pre-index), n (%)
  Anemia 547 (29.6) 154 (30.3) 349 (28.8) 0.527
  Anxiety 286 (15.5) 84 (16.5) 184 (15.2) 0.480
  Ischemia 386 (20.9) 111 (21.9) 249 (20.5) 0.544
  Cerebrovascular diseases 189 (10.2) 49 (9.6) 128 (10.6) 0.569
  Depression 236 (128) 70 (13.8) 156 (12.9) 0.611
  Hypertension 1253 (67.8) 310 (61) 877 (72.4) < 0.001
  Renal disease including ESRD 306 (16.6) 90 (17.7) 192 (15.8) 0.338
  Diabetes Mellitus 502 (27.2) 122 (24) 354 (29.2) 0.028
  Pneumonia 189 (10.2) 56 (11) 113 (9.3) 0.280
 Comorbidity Index, median [IQR]   8 [4.5] 8 [1] 0.002
  High deyo Charlson comorbidity score (score ≥ 7), n (%) 1404 (6.0) 368 (72.4) 944 (77.9) 0.015
Healthy Days
 Frequent overall unhealthy days, n (%) 823 (46.2) 245 (52.8) 531 (44.1) 0.001
 Frequent mental unhealthy days, n (%) 401 (22.8) 139 (30.3) 241 (20.2) < 0.001
 Frequent physical unhealthy days, n (%) 614 (34.9) 179 (38.7) 399 (33.6) 0.049
 Patient-reported excellent, very good or good health, n (%) 993 (55.9) 243 (52.4) 678 (56.4) 0.138
 Physical/mental health frequently impeded activities, n (%) 518 (29.5) 161 (35.0) 329 (27.7) 0.004
  1. Morisky Medication Adherence Score < 6 was defined as low comorbidity medication adherence
  2. Morisky Medication Adherence Score = 6, 7 or 8 was defined as moderate/high medication adherence
  3. Differences were assessed using a t-test for continuous variables and a chi-square test for categorical variables