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Table 5 Changes in CLDQ score by NASH status in patients with and without significant weight loss (Tapper and Lai, 2016) [14]

From: Health-related quality of life burden of nonalcoholic steatohepatitis: a robust pragmatic literature review

 

Patients with significant weight loss (n = 47)

Patients without significant weight loss (n = 104)

Patient subgroup

Change in CLDQ score

p-value

Change in CLDQ score

p-value

NASH (NAFLD activity score > 4)

0.61 (0.29 to 0.94)

0.0007

0.01 (−0.14 to 0.33)

0.42

No NASH (NAFLD activity score ≤ 4)

0.13 (0.01 to 0.57)

0.04

0.004 (−0.20 to 0.10)

0.97

  1. All values are reported as median (IQR)
  2. Significant weight loss was defined as ≥ 5% reduction at 6 months