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Table 5 Changes in CLDQ score by NASH status in patients with and without significant weight loss (Tapper and Lai, 2016) [14]

From: Health-related quality of life burden of nonalcoholic steatohepatitis: a robust pragmatic literature review

  Patients with significant weight loss (n = 47) Patients without significant weight loss (n = 104)
Patient subgroup Change in CLDQ score p-value Change in CLDQ score p-value
NASH (NAFLD activity score > 4) 0.61 (0.29 to 0.94) 0.0007 0.01 (−0.14 to 0.33) 0.42
No NASH (NAFLD activity score ≤ 4) 0.13 (0.01 to 0.57) 0.04 0.004 (−0.20 to 0.10) 0.97
  1. All values are reported as median (IQR)
  2. Significant weight loss was defined as ≥ 5% reduction at 6 months