Table 1 Patient demographics and clinical characteristics
Patients with ACO (n = 20) | Patients with COPD (n = 10) | Total (n = 30) | |
|---|---|---|---|
Demographics | |||
Age (years), mean (range) | 58.5 (45–72) | 64.4 (52–79) | 60.5 (45–79) |
Gender, % (n) | |||
Male | 65 (13) | 60 (6) | 63 (19) |
Ethnicity, % (n) | |||
Not Hispanic/Latino | 95 (19) | 90 (9) | 93 (28) |
Race, % (n) | |||
African American/African | 10 (2) | 30 (3) | 17 (5) |
White – Arabic/North African | 5 (1) | – | 3 (1) |
White – White/Caucasian/European | 80 (16) | 60 (6) | 73 (22) |
Other: White | – | 10 (1) | 3 (1) |
No response | 5 (1) | – | 3 (1) |
Education, % (n)a | |||
Some high school | 15 (3) | 20 (2) | 17 (5) |
High school diploma/GED | 20 (4) | 50 (5) | 30 (9) |
Some years of college | 35 (7) | – | 23 (7) |
Certificate program | 10 (2) | 10 (1) | 10 (3) |
University/college degree (2 or 4 year) | 20 (4) | 20 (2) | 20 (6) |
Vocational training | 10 (2) | – | 7 (2) |
Work status, % (n)a | |||
Working full time | 55 (11) | 10 (1) | 40 (12) |
Looking for work | – | 10 (1) | 3 (1) |
Full-time homemaker | 5 (1) | – | 3 (1) |
Not working due to respiratory condition | 15 (3) | 10 (1) | 13 (4) |
Retired | 20 (4) | 50 (5) | 30 (9) |
Other: disabled or odd jobs around neighborhood | 5 (1) | 20 (2) | 10 (3) |
General health, % (n) | |||
Very good | 10 (2) | 10 (1) | 10 (3) |
Good | 55 (11) | 50 (5) | 53 (16) |
Fair | 30 (6) | 30 (3) | 30 (9) |
Poor | 5 (1) | 10 (1) | 7 (2) |
MMRC dyspnea scale, % (n)a | |||
0 | 50 (10) | 30 (3) | 43 (13) |
1 | 55 (11) | 70 (7) | 60 (18) |
2 | 20 (4) | 30 (3) | 23 (7) |
3 | 15 (3) | 20 (2) | 17 (5) |
Clinical characteristics | |||
Primary disease, % (n) | |||
Asthma | 45 (9) | – | 30 (9) |
COPD type: Chronic bronchitis | 55 (11) | 100 (10) | 70 (21) |
COPD type: Emphysema | 10 (2) | 50 (5) | 23 (7) |
First use of a maintenance therapy inhaler (years) | |||
Mean (range) | 40.5 (14–64) | 42 (8–60) | 42 (8–64) |
Asthma diagnosis, % (n) | |||
Yes | 60 (12) | 40 (4) | 80 (16) |
Mean (range) age when first diagnosed | 23 (5–62) | 30.5 (1–57) | 25 (1–62) |
COPD diagnosis, % (n) | |||
Yes | 65 (13) | 100 (10) | 77 (23) |
Mean (range) age when first diagnosed | 49 (25–63) | 52.5 (38–71) | 50 (25–71) |
Smoking history, % (n) | |||
Never smoked | 25 (5) | – | 16 (5) |
Current smoker | 25 (5) | 60 (6) | 37 (11) |
Former smoker | 50 (10) | 40 (4) | 47 (14) |
Smoking history, pack years | |||
Mean (range) | 35 (4–92)b | 56 (33–90)c | 43 (4–92) |
Exacerbations that required corticosteroids | |||
In the last 12 months, n | 10 | 1 | 11 |
Mean (range) | 0.9 (0–4) | 0.1 (0–1) | 0.6 (0–4) |
In the last 3 months (n) | 3 | 0 | 3 |
Mean (range) | 0.15 (0–1) | – | 0.1 (0–1) |
Exacerbations that required hospitalization | |||
In the last 12 months (n) | 2 | 2 | 4 |
In the last 3 months (n) | 0 | 1 | 1 |
Lung function FEV1 (% predicted), mean (range) | 54 (1.6–68) | 50 (1–79) | 53 (1–79) |
Reversibility (L), mean (range) | |||
Pre-albuterol lung function (L in FEV1) | 1.7 (1.1–2.7) | 1.7 (1.1–2.6) | 1.7 (1.1–2.7) |
Post-albuterol lung function (L in FEV1) | 2.1 (1.3–3.1) | 1.7 (0.8–2.5) | 1.9 (0.8–3.1) |
Percent change | 19.2 (11.5–38.2) | 0.2 (−23.1–7.8) | 12.8 (−23.1–38.2) |
Clinician rated severity of COPD, % (n) | |||
Moderate | 100 (20) | 70 (7) | 90 (27) |
Severe | – | 30 (3) | 10 (3) |