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Table 4 Pearson correlation coefficients between symptom assessment by the PRO-CTCAE versus the EORTC QLQ-C30

From: The Japanese version of the National Cancer Institute’s patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE): psychometric validation and discordance between clinician and patient assessments of adverse events

 

EORTC QLQ-C30

PRO-CTCAE items at Visit 1

Fatigue

Nausea/Vomiting

Pain

Dyspnea

Insomnia

Appetite loss

Constipation

Diarrhea

Fatigue, tiredness, or lack of energy, Severity

0.56

0.35

0.28

0.20

0.21

0.48

0.11

0.18

Fatigue, tiredness, or lack of energy, Interference

0.59

0.39

0.32

0.27

0.20

0.49

0.02

0.13

Nausea, Frequency

0.32

0.76

0.25

0.15

0.17

0.36

0.22

0.24

Nausea, Severity

0.33

0.77

0.27

0.09

0.15

0.38

0.16

0.27

Vomiting, Frequency

0.15

0.64

0.13

0.11

0.10

0.20

0.16

0.18

Vomiting, Severity

0.16

0.63

0.16

0.07

0.14

0.18

0.09

0.18

Pain, Frequency

0.21

0.10

0.65

0.04

0.25

0.14

0.12

0.06

Pain, Severity

0.27

0.11

0.70

0.09

0.31

0.16

0.07

0.10

Pain, Interference

0.32

0.11

0.69

0.07

0.30

0.26

0.06

0.14

Shortness of breath, Severity

0.39

0.10

0.11

0.66

0.12

0.13

0.03

−0.04

Shortness of breath, Interference

0.42

0.10

0.23

0.64

0.19

0.10

0.05

−0.03

Insomnia, Severity

0.26

0.17

0.24

0.16

0.62

0.22

0.16

0.27

Insomnia, Interference

0.33

0.16

0.28

0.21

0.67

0.29

0.17

0.24

Decreased appetite, Severity

0.45

0.51

0.30

0.13

0.28

0.71

0.14

0.30

Decreased appetite, Interference

0.49

0.48

0.38

0.14

0.34

0.69

0.11

0.32

Constipation, Severity

0.02

0.12

0.10

−0.04

0.16

0.10

0.65

0.06

Loose or watery stools (diarrhea), frequency

0.14

0.15

0.12

0.09

0.20

0.21

−0.01

0.71

  1. Bold: Corresponding item between the ELRTC QLQ-C30 and PRO-CTCAE