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Table 1 Baseline demographic and clinical characteristics in the concept elicitation interviews of Stage 1

From: Qualitative interviews of patients with COPD and muscle weakness enrolled in a clinical trial evaluating a new anabolic treatment: patient perspectives of disease experience, trial participation and outcome assessments

 

Total (N = 20)

Age (years), mean (SD)

64.2 (9.5)

Female, n (%)

12 (60.0)

Race, n (%)

 

 White/Caucasian

 Black African or Caribbean

10 (50.0)

10 (50.0)

Clinical characteristics

Time since COPD diagnosis (months), mean (SD)

45.1 (27.6)

Time since muscle weakness diagnosis (months), mean (SD)

22.9 (15.4)

Baseline predicted FEV1(%), mean (SD)

50.1 (11.2)

Predicted FEV1, n (%)

 

 20–29%

 30–39%

 40–49%

 50–59%

 60–69%

 70–80%

1 (5)

2 (10)

4 (20)

10 (50)

2 (10)

1 (5)

BMI (kg/m2), mean (SD)

26.6 (3.6)

COPD exacerbations since diagnosis, n (%)

 

 0

 1

 2

 3

6 (30.0)

9 (45.0)

3 (15.0)

2 (10.0)

Patients hospitalized in the past 12 months, n (%)

 

 0

 1

 2

15 (75.0)

3 (15.0)

2 (10.0)

CAT score, mean (SD)

20.3 (6.9)

Current treatments for COPD, n (%)

 

 ICS

 LABA

 LAMA

19 (95.0)

20 (100.0)

11 (55.0)

Severity of muscle weakness condition, n (%)

 

 Mild

 Moderate

 Severe

8 (40.0)

9 (45.0)

3 (15.0)

  1. BMI, body mass index; CAT, COPD Assessment Test; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; ICS, inhaled corticosteroids; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; SD, standard deviation