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Table 3 EQ-5D-5L index values, EQ VAS and the EQ-5D-5L descriptive system for patients with active and inactive IBD

From: Construct validity of EQ-5D-5L among patients with inflammatory bowel disease—a study based on real-world data from the Swedish Inflammatory Bowel Disease Registry

  

Crohn’s disease (n = 4080)

Ulcerative colitis (n = 5110)

Total (n = 9651)

Inactive n = 2747 (100%)

Active n = 1333 (100%)

 

Inactive n = 3550 (100%)

Active n = 1560 (100%)

 

Inactive n = 6592 (100%)

Active n = 3059 (100%)

 
 

Mean EQ-5D index

0.83

0.67

p<0.001

0.85

0.71

p<0.001

0.84

0.69

p<0.001

 

Mean EQ VASa

78.50

63.36

p<0.001

79.72

66.59

p<0.001

79.06

64.87

p<0.001

Mobility

No problems (%)

82.1

68.0

p<0.001

z = −10.5

r = 0.16

83.9

76.3

p<0.001

z = −6.6

r = 0.09

82.8

72.6

p<0.001

z = −12.0

r = 0.12

Slight problems (%)

11.6

16.7

10.0

13.6

10.7

15.0

Moderate problems (%)

4.7

10.9

4.2

7.0

4.6

8.7

Severe problems (%)

1.6

4.1

1.6

2.8

1.6

3.4

Unable (%)

0.1

0.3

0.3

0.3

0.2

0.3

Self-Care

No problems (%)

95.5

89.0

p<0.001

z = −7.9

r = 0.12

95.6

92.5

p<0.001

z = −4.5

r = 0.06

95.4

91.1

p<0.001

z = −8.3

r = 0.08

Slight problems (%)

3.2

7.1

3.1

5.4

3.3

6.0

Moderate problems (%)

0.9

3.1

0.8

1.4

0.8

2.1

Severe problems (%)

0.3

0.7

0.5

0.6

0.4

0.6

Unable (%)

0.1

0.2

0.1

0.1

0.1

0.1

Usual activities

No problems (%)

74.8

46.5

p<0.001

z = −18.8

r = 0.29

80.2

50.7

p<0.001

z = −22.3

r = 0.31

77.8

48.8

p<0.001

z = −29.9

r = 0.30

Slight problems (%)

16.1

27.0

13.2

25.1

14.5

26.0

Moderate problems (%)

6.7

14.9

4.3

14.0

5.3

14.4

Severe problems (%)

1.7

8.9

1.6

7.0

1.7

7.8

Unable (%)

0.7

2.8

0.6

3.1

0.7

2.9

Pain/discomfort

No (%)

49.9

19.7

p<0.001

z = −22.3

r = 0.35

57.2

23.5

<0.001

z = −23.6

r = 0.33

53.7

21.7

p<0.001

z = −32.9

r = 0.34

Slight (%)

30.8

30.8

27.4

38.7

28.6

34.7

Moderate (%)

15.8

35.5

12.3

27.6

14.3

31.5

Severe (%)

3.1

12.3

2.9

9.4

3.1

10.7

Extreme (%)

0.3

1.8

0.2

0.8

0.3

1.4

Anxiety/depression

Not (%)

54.5

29.4

p<0.001

z = −17.4

r = 0.27

59.8

30.3

<0.001

z = −21.5

r = 0.30

57.3

30.1

p<0.001

z = −28.0

r = 0.28

Slightly (%)

33.6

40.4

30.2

40.6

31.6

40.4

Moderately (%)

9.1

18.4

7.4

19.9

8.3

19.3

Severely (%)

2.1

8.4

2.1

7.8

2.1

8.0

Extremely (%)

0.7

3.5

0.5

1.4

0.7

2.3

  1. EQ VAS n CD: 2 388 (inactive disease), 1 162 (active disease). EQ VAS n UC: 3 080 (inactive), 1 310 (active). EQ VAS n Total: 5 691 (inactive), 2 594 (active)
  2. r effect size, Z Z-score Mann-Whitney U test, p p-value
  3. aDue to missing values, the number of patients (n) with EQ VAS score were lower