Health-related quality of life questionnaires | Domains | Description and scoring |
---|---|---|
EORTC QLQ-C30 (30) | Global quality of life Five functional domains (physical, role, emotional, cognitive and social) Nine symptom domains (fatigue, nausea and vomiting, pain, dyspnoea, insomnia, appetite loss, constipation, diarrhea) Financial difficulties | A 30-item, 15 domain cancer-generic questionnaire validated in patients with multiple myeloma (31). Recall period of 7 days. Four-point categorical scale: ‘not at all’, ‘a little’, ‘quite a bit’, ‘very much’. The answers are transformed into 0-100 scales (44). For the functional domains, a high score means low degree of problems. For the symptom domains, a high score means high degree of symptoms. |
EORTC QLQ-MY20 (32) | Two functional domains (future perspective and body image) Two symptom domains (disease symptoms and side effects of treatment) | A 20-item, four domain myeloma-specific questionnaire. Recall period of 7 days. Four-point categorical scale: ‘not at all’, ‘a little’, ‘quite a bit’, ‘very much’. The answers are transformed into 0-100 scales (44). For the functional domains, a high score means low degree of problems. For the symptom domains, a high score means high degree of symptoms. |
FACT/GOG-ntx (33) | Peripheral neuropathy | An 11-item questionnaire summarized as a single domain of peripheral neuropathy. Recall period of 7 days. Five-point categorical scale: ‘not at all’, ‘a little bit’, ‘somewhat’, ‘quite a bit’, ‘very much’. The answers are transformed into a 0–44 scale (45). Higher score indicating less peripheral neuropathy |