Table 3 Determination of the minimal clinically important difference in PROMIS PF20a scores
Subject’s global impression of change in overall well-being between 0 and 52 weeks | Number of patients (%) | Change in PROMIS PF20a from 0 to 52 weeks, mean (SD) |
|---|---|---|
1: very much worse | 0 (0.0) | N/A |
2: much worse | 4 (3.4) | -2.8 (7.9) |
3: somewhat worse | 19 (16.2) | -3.4 (7.5) |
4: no change | 45 (38.5) | 2.2 (10.0) |
5: somewhat improved | 36 (30.8) | 2.4 (6.7) |
6: much improved | 8 (6.8) | 4.4 (5.1) |
7: very much improved | 5 (4.3) | 8.5 (11.9) |